Stories of Discovery, Innovation, and Impact
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Neurology

Tuberculosis Vaccine Changes Brain’s Immune Environment and Alzheimer’s Biomarkers in Older Adults

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Cancer
Genetic Makeup Affects Whether Patients Experience Benefits or Side Effects of Immune Cell Therapy for Cancer
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Heart Conditions
Mass General Brigham Researchers Awarded ARPA-H Funding to Scale Genome Editing for Rare Genetic Vascular Diseases
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Featured Story

Preclinical Study Suggests Restoring Inhibitory Neuron Plasticity May Reverse Neurodevelopmental Disorder Symptoms

A team led by investigators at Mass General Brigham identified genes involved in these neurons’ plasticity and then demonstrated benefits to overexpressing one key gene.

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Shown in yellow, a parvalbumin interneuron in hippocampal CA3/CA2. Credit: Sahay lab.

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About Mass General Brigham Research

Transforming Discovery Together

We drive transformative innovation in an environment where the best and the brightest researchers, clinicians, staff, and trainees collaborate across the enterprise and with partners around the world. Patients are at the center of what we do; we shape the future of biomedical research to create revolutionary solutions to improve the health of people everywhere.
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Who we are
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Clinical Research

Advancing patient-centered research and innovation

We know the importance of research and innovation, and our patients' role in it. Our founding hospitals have a long tradition of medical breakthroughs, and you can be a part of the next discovery.
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Explore clinical research opportunities
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$2.7 billion+

annual research budget

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14

Nobel Laureats

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200+

years of leading innovative science

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As a world-recognized leader in research, Mass General Brigham is home to one of the largest hospital system-based research medical centers in the U.S. Our researchers and clinicians are conducting thousands of studies in every major medical therapeutic and technology discipline.
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No. 1

among 60 organizations and centers in the Cure Innovation Index

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