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Musculoskeletal Oncology Fellowship
The Musculoskeletal Oncology Fellowship at Mass General Brigham provides exposure to the many facets of orthopaedic oncology through our multidisciplinary group of clinicians.
secondary
phone
Call: 617-724-8801
6177248801
tertiary
email
Email: fviazzoli@mgh.harvard.edu
fviazzoli@mgh.harvard.edu
Overview
The Massachusetts General Hospital Orthopaedic Oncology Fellowship is a one-year, high-volume, multidisciplinary program jointly based at Massachusetts General Hospital and Boston Children’s Hospital. Fellows gain experience in diagnosing and treating benign and malignant bone and soft-tissue tumors through operative and non-operative care. In addition to surgical training in limb-salvage, reconstruction, amputation, and metastatic disease management, fellows learn to coordinate with multiple disciplines, including medical oncology, radiation oncology, pathology, and radiology. Teaching is a core component. Fellows present weekly during surgical indications, lead focused educational sessions for residents, and participate in monthly journal clubs.
Curriculum
The curriculum runs year-round and is divided into seven thematic blocks. Each block combines lectures, journal clubs, and dedicated radiology and pathology sessions, fostering multidisciplinary learning and collaboration. Every session is led by expert faculty from orthopaedic oncology, radiology, pathology, medical oncology, or radiation oncology. The curriculum complements intensive clinical and operative experience, ensuring fellows graduate prepared for independent orthopaedic oncology practice.
Didactic Blocks
- General Evaluation and Treatment – Foundations of musculoskeletal oncology, including tumor workup, biopsy principles, staging, and imaging interpretation.
- Malignant Bone Tumors – Management of osteosarcoma, Ewing sarcoma, chondrosarcoma, chordoma, and metastatic bone disease, emphasizing surgical decision-making, systemic therapy, and multidisciplinary planning.
- Lymphoma & Myeloma – Diagnosis and treatment of hematologic bone tumors, integrating pathology, imaging, chemotherapy, and radiation therapy.
- Malignant Soft Tissue Tumors – Imaging, pathology, and treatment of sarcomas such as synovial, liposarcoma, leiomyosarcoma, and angiosarcoma, with focus on multimodal therapy and advanced molecular classification.
- Benign Bone Tumors – Evaluation and management of cartilage, cystic, fibrous, and histiocytic lesions, including the use of bone grafts, substitutes, and targeted therapies like denosumab.
- Benign Soft Tissue Tumors – Approach to lipomatous, vascular, neural, and fibrous soft tissue lesions, emphasizing imaging-pathology correlation and indications for surgery.
- Metabolic Bone Disease & Surgical Topics – Advanced reconstructive and surgical principles including limb-sparing techniques, amputation with targeted muscle reinnervation, rotationplasty, allograft and endoprosthetic reconstruction, and management of metastatic and metabolic bone disease.
See the 2025-2026 curriculum blocks
Why Train at Mass General
The Orthopaedic Oncology Service at Mass General is busy clinical service with a large volume of patients and conditions, enriching the experience of the fellows in the program. The high volume improves the surgical training, practice and repetition of surgical techniques. The infrastructure as a tertiary referral cancer care center facilitates exposure to the different subspecialties involved in the multidisciplinary care and management required by the oncologic patient population. The frequent interaction with plastic surgery, vascular surgery, thoracic oncology surgery, urology and surgical oncology enriches the experience of our fellows and expands their knowledge and experience.
The constant interaction with musculoskeletal radiologists, bone and soft tissue pathologists, sarcoma oncologist and radiation oncologists, enriches the academic conferences and clinical discussions for our fellowship trainees. Compared to other centers and fellowships, our program has a very balanced combination of adult and pediatric patients in addition to significant exposure to pelvic and sacral surgery as well as spine oncology.
Members of our faculty are pioneers in surgical technique development and innovations allowing the fellowship trainees to familiarize with new technologies such as carbon fiber implants, photodynamic nails, custom made implants for pelvic reconstruction, intraoperative ICG dye for sarcoma surgery amongst other. The number of faculty offers variety in surgical technique and strategies for patient management.
The multiple academic conferences offer protected time for fellow trainee education, which allows time for learning despite a busy clinical day-to-day.
For research, the fellowship program has a series of ongoing clinical research and basic science projects that provide opportunity to be involved in the design of studies and protocols, database management and data analysis, and finalization and writing of manuscripts. Fellows in our program are expected to complete one original article during the fellowship year.
Conferences
A series of conferences take place on a weekly and monthly basis. The weekly conferences include:
- Indications Conference: Preoperative review of the surgical cases of the week and the indications for each procedure.
- Resident Teaching Conference: Resident-led presentation in a flexible format of musculoskeletal oncology topics relevant to orthopedists as a whole.
- Musculoskeletal Radiology Conference: Multidisciplinary conference where different cases from clinics are presented to discuss biopsy approaches, follow-up and additional work up strategies, rare conditions and classic clinical/radiologic scenarios with learning value.
- Fellow Teaching Conference: One-hour long duration multidisciplinary conference in which a multidisciplinary presentation is given by faculty from different services focusing in benign and malignant musculoskeletal oncologic conditions are review along with their medical and surgical treatment.
These conferences include faculty from the bone and soft tissue pathology service, musculoskeletal radiology division, radiation oncology and medical oncology departments, and the orthopaedic oncology service. Lastly, a Sarcoma Tumor Board Meeting takes place in both rotations for the multidisciplinary discussion and management of sarcoma patients. In this conference adjuvant and neoadjuvant treatment plans are discussed and reviewed as well as surgical plans and final margin status.
Monthly conferences include Journal Club and the department Morbimortality meeting. The Journal Club is led by the fellowship trainees. Both fellows select topics and articles for discussion with the participating faculty in this meeting.
Special Programs
In addition to the musculoskeletal oncology service, our fellows can participate in the ICAN Clinic (management of patients with amputations), the pediatric and adult oncology clinics, radiation oncology treatments and clinic including the proton radiation center and the musculoskeletal radiology service on days of procedures and biopsies.
Research Experience
There are two independent research units in our program. One covers research that takes place at Children’s Hospital and BIDMC, with one research coordinator at each hospital, and one covers research at Mass General, which has three research coordinators. Most of the research is clinical in nature, focusing in clinical outcomes, surgical techniques, diagnostic tools, application of machine learning to prognosis calculators in musculoskeletal oncology and the use of new implants for surgical reconstruction. The use megaprosthetic, allograft reconstruction or a combination of the two (alloprosthesis), is one the biggest pillars of research at both sites focusing particularly in complications such as infection. There are few studies that are sponsored by companies with the majority of studies being investigator initiated. Both sites have infrastructure for biomechanical studies and at MGH, Dimitiris Spentzos, MD, leads research dedicated to micro-RNA extraction and analysis through bioinformatics.
Support Resources for Research
Support resources for research include research coordinators, biomechanical laboratories at both Mass General (with the Foot & Ankle Research and Innovation Lab (FARIL)) and BIDMC; basic science laboratories in microRNA and bioinformatics; as well as other basic science laboratories at Mass General and the Martinos Research Institute; machine learning laboratory and initiative at Mass General; and Biostatistical support by the Harvard Catalyst Institute.
Recent publications
- Morse AS, Gonzalez MR, Kang HP, Lozano-Calderon SA. ASO Visual Abstract: Comparison of Percutaneous Techniques for Stabilization of Osteolytic Lesions of the Periacetabular Region due to Metastatic Bone Disease. Ann Surg Oncol. 2025 Jan 8. doi: 10.1245/s10434-024-16779-4. Epub ahead of print. PMID: 39779581.
- Goh MH, Rabiner RA, Connolly JJ, Lozano-Calderon SA, Chen AF. A Novel Isotropic Optical Fiber: Antimicrobial Effect of Blue Light on Drug Resistant Organisms. J Orthop Res. 2025 Jan 7. doi: 10.1002/jor.26042. Epub ahead of print. PMID: 39775972.
- Jeys LM, Morris GV, Kurisunkal VJ, Botello E, Boyle RA, Ebeid W, Houdek MT, Puri A, Ruggieri P, Brennan B; BOOM Consensus Meeting Participants; Laitinen MK. Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting. Bone Joint J. 2025 Feb 1;107-B(2):246-252. doi: 10.1302/0301-620X.107B2.BJJ-2024-0643.R1. PMID: 39889743.
- Goh MH, Gonzalez MR, Heiling HM, Mazzola E, Connolly JJ, Choy E, Cote GM, Spentzos D, Lozano-Calderon SA. Adjuvant chemotherapy in localized, resectable extremity and truncal soft tissue sarcoma and survival outcomes - A systematic review and meta-analysis of randomized controlled trials. Cancer. 2025 Mar 1;131(5):e35792. doi: 10.1002/cncr.35792. PMID: 40023772.
- Goh MH, Connolly JJ, Chen AF, Rabiner RA, Lozano-Calderon SA. Antimicrobial effect of blue light on antibiotic-sensitive and drug-resistant Escherichia coli: a novel isotropic optical fibre. Access Microbiol. 2025 Mar 19;7(3):000967.v3. doi: 10.1099/acmi.0.000967.v3. PMID: 40114681; PMCID: PMC11923094.
- Coan JM, Gasho JO, Connolly JJ, Lozano-Calderon SA, Raskin KA, Schwab JH, Tobert DG. Long-Term Bladder, Bowel, and Ambulatory Function After Sacrectomy Surgery. Spine (Phila Pa 1976). 2025 Mar 17. doi: 10.1097/BRS.0000000000005326. Epub ahead of print. PMID: 40091260.
- Gonzalez MR, Kuthiala RS, Newman ET, Raskin KA, Lozano-Calderon SA. What Is the Diagnostic Performance and Accuracy of Serum Inflammatory Biomarkers and Synovial Fluid Analysis in Megaprosthetic Periprosthetic Joint Infections? J Arthroplasty. 2025 Apr 8:S0883-5403(25)00335-3. doi: 10.1016/j.arth.2025.04.009. Epub ahead of print. PMID: 40209824.
- Taseh A, Sirls E, Casey G, Hearns S, Doornberg JN, Lozano-Calderon SA, Harris MB, Ashkani-Esfahani S. Social vulnerability index enhances FRAX prediction of hip fractures in fall patients. Sci Rep. 2025 Apr 27;15(1):14704. doi: 10.1038/s41598-025-99373-2. PMID: 40289226; PMCID: PMC12034780.
- van der Linden LR, Vavliakis I, de Groot TM, Jutte PC, Doornberg JN, Lozano-Calderon SA, Groot OQ. Artificial Intelligence in bone Metastases: A systematic review in guideline adherence of 92 studies. J Bone Oncol. 2025 Apr 24;52:100682. doi: 10.1016/j.jbo.2025.100682. PMID: 40337637; PMCID: PMC12056386.
- Connolly JJ, Goh MH, Lim P, Gonzalez MR, Bedair HS, Melnic CM, Lozano-Calderón SA. How Do the Outcomes of Total Hip Arthroplasty for Oncologic Hip Reconstruction Compare With Those Performed for End-Stage Osteoarthritis?-A Propensity-Matched Cohort Study. J Am Acad Orthop Surg. 2025 Apr 24. doi: 10.5435/JAAOS-D-24-01124. Epub ahead of print. PMID: 40311143.
- Bedi AD, Gonzalez MR, van der Linden LR, Lozano-Calderon SA. Reply to: Comment on: Incidence and survival outcomes of patients with high-grade appendicular bone sarcoma and isolated regional lymph node metastasis: A national cohort database study. Eur J Surg Oncol. 2025 Apr 12:110035. doi: 10.1016/j.ejso.2025.110035. Epub ahead of print. PMID: 40246641.
- Zamora T, Botello E, Jenkins T, Jeys C, Laitinen M, Puri A, Jeys L; BOOM consensus meeting participants. Global and regional disparities in access to specialist sarcoma services. Bone Jt Open. 2025 Apr 11;6(4):425-431. doi: 10.1302/2633-1462.64.BJO-2024-0208.R1. PMID: 40210212; PMCID: PMC11985170.
- Goh MH, Jejurikar N, Gonzalez MR, Lozano-Calderon SA. Augmentation of Osteoarticular Allograft Reconstruction With Photodynamic Nail for the Management of Primary or Recurrent Aggressive Giant Cell Tumor in the Distal Radius. J Hand Surg Glob Online. 2025 May 20;7(4):100726. doi: 10.1016/j.jhsg.2025.02.016. PMID: 40497272; PMCID: PMC12148489.
- Gonzalez MR, Okay E, Werenski JO, Connolly JJ, Pfeiffer A, Newman ET, Raskin KA, Lozano-Calderón SA. What Are the Long-Term Clinical and Functional Outcomes After Hemicortical Allograft Reconstruction for Primary Bone Tumors? J Surg Oncol. 2025 May 13. doi: 10.1002/jso.28147. Epub ahead of print. PMID: 40358135.
- Clunk MJ, Gonzalez MR, Ubong SE, Sodhi A, Werenski JO, Denwood HM, Tobert DG, Lozano-Calderon SA. Early experience with percutaneous photodynamic nails for sacral metastatic disease and insufficiency fractures: a retrospective cohort analysis of functionality and pain relief. BMC Musculoskelet Disord. 2025 May 10;26(1):460. doi: 10.1186/s12891-025-08707-8. PMID: 40349021; PMCID: PMC12066073.
- Raasveld FV, Hanna T, Pacheco FJ, Gonzalez MR, Johnston B, Lozano-Calderón SA, Valerio IL, Eberlin KR. Neuropathic Pain Following Surgery for Malignant Peripheral Nerve Sheath Tumors. Ann Surg Oncol. 2025 May;32(5):3741-3751. doi: 10.1245/s10434-025-17001-9. Epub 2025 Feb 22. PMID: 39987385.
- Raasveld FV, Hanna T, Pacheco FJ, Gonzalez MR, Johnston B, Lozano-Calderón SA, Valerio IL, Eberlin KR. ASO Author Reflections: Neuropathic Pain-A Persistent Challenge Following Surgical Resection of Malignant Peripheral Nerve Sheath Tumors. Ann Surg Oncol. 2025 May;32(5):3766-3767. doi: 10.1245/s10434-025-17124-z. Epub 2025 Mar 9. PMID: 40057647.
- Khela HS, DePalo J, Merkely GB, Kishan A, Petrigliano FA, Mazzocca AD, Passias PG, Lozano-Calderón SA, Levine WN, Kishan A. Comorbidity-specific long-term complication risks on postoperative outcomes in total shoulder arthroplasty. J Shoulder Elbow Surg. 2025 Jun 13:S1058-2746(25)00477-X. doi: 10.1016/j.jse.2025.05.010. Epub ahead of print. PMID: 40517942.
- Goh MH, Ballatori SE, Gonzalez MR, Lozano-Calderon SA. Management of Impending and/or Pathologic Fractures of the Proximal Radius in the Setting of Metastatic Bone Disease With an Intramedullary Photodynamic Nail. Tech Hand Up Extrem Surg. 2025 Jun 1;29(2):e00513. doi: 10.1097/BTH.0000000000000513. PMID: 40150940.
- Werenski JO, Su MW, Krueger RK, Groot OQ, Clunk MJ, Sodhi A, Patil R, Bell N, Levin AS, Lozano-Calderon SA. An External Validation of the Pathologic Fracture Mortality Index for Predicting 30-day Postoperative Morbidity Using 978 Institutional Patients. J Am Acad Orthop Surg. 2025 Jun 1;33(11):e615-e624. doi: 10.5435/JAAOS-D-24-01131. Epub 2025 Apr 1. PMID: 40179363.
- Segu HV, Rampam S, Gonzalez MR, Gebhardt NM, Chebib I, Hung YP, Lozano-Calderon SA. ASO Visual Abstract: Comparison of Local Recurrence Rates between Wide Resection and Expanded Marginal Excision in Atypical Lipomatous Tumors. Ann Surg Oncol. 2025 Jun 17. doi: 10.1245/s10434-025-17715-w. Epub ahead of print. PMID: 40526343.
- Segu HV, Rampam S, Gonzalez MR, Gebhardt NM, Chebib I, Hung YP, Lozano-Calderon SA. Comparison of Local Recurrence Rates Between Wide Resection and Expanded Marginal Excision in Atypical Lipomatous Tumors. Ann Surg Oncol. 2025 Jun 9. doi: 10.1245/s10434-025-17606-0. Epub ahead of print. PMID: 40490638.
- Patel RV, Gonzalez MR, Attaar N, Patel MV, Lozano-Calderon SA. Analyzing Orthopaedic Workforce Trends in an Ever-changing Landscape. J Am Acad Orthop Surg. 2025 Jun 6. doi: 10.5435/JAAOS-D-24-00797. Epub ahead of print. PMID: 40523164.
- Segu HV, Gonzalez MR, Rampam S, Gebhardt NM, Chebib I, Hung YP, Lozano-Calderon SA. ASO Author Reflections: Comparison of Local Recurrence Rates between Wide Resection and Expanded Marginal Excision in Atypical Lipomatous Tumors. Ann Surg Oncol. 2025 Jul 3. doi: 10.1245/s10434-025-17758-z. Epub ahead of print. PMID: 40608167.
- Leland CR, Gonzalez MR, Werenski JO, Vallone AT, Brighton KG, Newman ET, Lozano-Calderón SA, Raskin KA. Reply to the Letter to the Editor: What Factors Are Associated With Implant Revision in the Treatment of Pathologic Subtrochanteric Femur Fractures? Clin Orthop Relat Res. 2025 Oct 1;483(10):1989-1991. doi: 10.1097/CORR.0000000000003635. Epub 2025 Jul 23. PMID: 40762632; PMCID: PMC12453351.
- Kishan A, Kubsad S, Wang JY, Nguyen D, Lozano-Calderón SA, Srikumaran U, Best MJ. Trends in Extended Oral Antibiotic Prophylaxis after Primary Total Shoulder Arthroplasty, 2010–2021. Seminars in Arthroplasty: JSES 2025. https://doi.org/10.1053/j.sart.2025.06.007.
- Groot TM, van der Linden LR, Bedi ADS, Lucaciu AA, Jang CC, Groot OQ, Doornberg JN, Jutte PC, Lozano-Calderon SA, Schwab JH. Social determinants are associated with clinical presentation of acute pathological fracture in metastatic long-bone disease. J Bone Oncol. 2025 Aug 5;54:100707. doi: 10.1016/j.jbo.2025.100707. PMID: 40810126; PMCID: PMC12343859.
- Gonzalez MR, Ubong SE, Jutte PC, Lozano-Calderon SA. Impact of Silver Coating on Periprosthetic Joint Infection Risk in Modular Endoprostheses Used in Primary and Revision Arthroplasty: A Systematic Review and Meta-Analysis. J Arthroplasty. 2025 Sep 11:S0883-5403(25)01165-9. doi: 10.1016/j.arth.2025.09.012. Epub ahead of print. PMID: 40945758.
- Girgis AG, Galoaa BM, Goh MH, Gonzalez MR, Lozano-Calderón SA. Bias or Best Fit? A Comparative Analysis of the SEER and NCDB Data Sets in Single-model Machine Learning for Predicting Osteosarcoma Survival Outcomes. Clin Orthop Relat Res. 2025 Sep 23. doi: 10.1097/CORR.0000000000003701. Epub ahead of print. PMID: 41056069.
- Girgis AG, Galoaa BM, Gonzalez MR, Lozano-Calderon SA. Advancing Prognostics in Oncology: Developing a Machine Learning Model for Predicting 2-Year and 5-Year Survival Rates in Patients with Undifferentiated Pleomorphic Sarcoma. Ann Surg Oncol. 2025 Sep 8. doi: 10.1245/s10434-025-18249-x. Epub ahead of print. PMID: 40921899.
- De Pena AM, Gonzalez MR, Connolly JJ, Lozano-Calderon SA. Long-Term Functional Outcomes and Modes of Failure of Fresh Frozen Hemicondylar Allografts: A Retrospective Cohort Study. J Surg Oncol. 2025 Sep 9. doi: 10.1002/jso.70081. Epub ahead of print. PMID: 40923897.
- Rampam S, Girgis AG, Galoaa BM, Werenski JO, Gonzalez MR, Lozano-Calderón SA. Predicting long term survival in myxofibrosarcoma: Development and evaluation of Machine learning models for 2- and 5-year outcomes. Surg Oncol. 2025 Oct 28;64:102314. doi: 10.1016/j.suronc.2025.102314. Epub ahead of print. PMID: 41175698.
- Wang CI, Giersch AB, Calderon SL, Choy E, Giap FN, Hung YP, Nielsen GP, Chebib I. "Benign" Metastasizing Fibrous Histiocytoma Harboring PRKCD Gene Fusions With Malignant Clinical Course. Genes Chromosomes Cancer. 2025 Nov;64(11):e70094. doi: 10.1002/gcc.70094. PMID: 41254746.
- van der Linden LR, Gonzalez MR, Gasho JO, Ubong SE, Elhassan BT, Kang HP, Lozano Calderón SA. Functional Outcomes of Reverse Shoulder Arthroplasty and Allograft-Prosthetic Composite in Oncologic Patients. J Am Acad Orthop Surg. 2025 Nov 11. doi: 10.5435/JAAOS-D-25-00466. Epub ahead of print. PMID: 41223435.
- Connolly JJ, Gonzalez MR, Davis JB, Moussaoui YH, Goh GS, Chen AF, Olsen AS, Lozano-Calderón SA. Microbiological profile of prosthetic joint infections in orthopedic oncology: a comparison with conventional joint arthroplasty. J Bone Jt Infect. 2025 Nov 18;10(6):459-469. doi: 10.5194/jbji-10-459-2025. PMID: 41278554; PMCID: PMC12634182.
- Gonzalez MR, Okay E, Werenski JO, Silva-Mancera SF, Connolly JJ, Pfeiffer A, Duggan J, Newman ET, Raskin KA, Ortiz-Cruz EJ, Lozano-Calderon SA. Long-Term Clinical and Functional Outcomes after Intercalary Allograft Reconstruction for Oncologic Indications. Ann Surg Oncol. 2025 Dec 2. doi: 10.1245/s10434-025-18819-z. Epub ahead of print. PMID: 41331172.
- Gonzalez MR, Werenski JO, Okay E, Lozano-Calderon SA. ASO Author Reflections: Long-Term Clinical and Functional Outcomes After Intercalary Allograft Reconstruction for Oncologic Indications. Ann Surg Oncol. 2025 Dec 27. doi: 10.1245/s10434-025-18970-7. Epub ahead of print. PMID: 41455842.
- Gonzalez MR, Okay E, Werenski JO, Silva-Mancera SF, Connolly JJ, Pfeiffer A, Duggan J, Newman ET, Raskin KA, Ortiz-Cruz EJ, Lozano-Calderon SA. ASO Visual Abstract: Long-Term Clinical and Functional Outcomes after Intercalary Allograft Reconstruction for Oncologic Indications. Ann Surg Oncol. 2026 Jan 12. doi: 10.1245/s10434-025-19061-3. Epub ahead of print. PMID: 41524874.
- Hoftiezer YAJ, Werenski JO, Posada Alvarez C, Lee SG, Lozano-Calderón SA. Bilateral elbow joint osteonecrosis reconstructed by custom distal humerus hemiarthroplasty and megaprosthesis with tendon and nerve transfers - A case report. JPRAS Open. 2026 Jan 31;49:35-40. doi: 10.1016/j.jpra.2026.01.039. PMID: 41768289; PMCID: PMC12938139.
- Girgis AG, Galoaa BM, Gonzalez MR, Lozano-Calderon SA. ASO Visual Abstract: Advancing Prognostics in Oncology: Developing a Machine Learning Model for Predicting 2-Year and 5-Year Survival Rates in Patients with Undifferentiated Pleomorphic Sarcoma. Ann Surg Oncol. 2026 Feb;33(2):1723-1724. doi: 10.1245/s10434-025-18748-x. PMID: 41247596.
- de Groot TM, Hendriks JRH, Shimizu MR, Te Velde JP, Groot OQ, Newman ET, Raskin K, Doornberg JN, Jutte PC, Lozano-Calderón S, Schwab JH. Post-operative survival and use of systemic therapy in metastatic long-bone disease: 12 years of institutional experience. J Bone Oncol. 2026 Feb 13;57:100751. doi: 10.1016/j.jbo.2026.100751. PMID: 41732250; PMCID: PMC12925594.
- Skornja I, Gonzalez MR, Hederick LL, Newman ET, Raskin KA, Lozano-Calderon SA. Treatment Success Rate After Surgical Management of Periprosthetic Joint Infections in Oncologic Proximal Tibia Reconstruction. J Surg Oncol. 2026 Feb 15. doi: 10.1002/jso.70210. Epub ahead of print. PMID: 41693290.
- Hederick LL, Goh MH, Ibáñez-Navarro A, Connolly JJ, Halur SR, Miller AR, Flood BA, Nielsen GP, Chang CY, Lozano-Calderón SA. Investigating possible predictors of malignant transformation of osteochondroma: a retrospective cohort study with an illustrative case report. Skeletal Radiol. 2026 Feb 11. doi: 10.1007/s00256-026-05162-x. Epub ahead of print. PMID: 41670645.
- Sood H, Gonzalez MR, Ubong SE, Lozano-Calderon SA. Long-Term Functional Outcomes and Survival Following Intramedullary Nailing of Pathological Diaphyseal Tibial Fractures. J Am Acad Orthop Surg. 2026 Mar 3. doi: 10.5435/JAAOS-D-25-00987. Epub ahead of print. PMID: 41791026.
- Werenski JO, Connolly JJ, Gonzalez MR, Okay E, Rizk PA, Karim DS, Raskin KA, Newman ET, Lozano-Calderon SA. Patient perspectives on recovery and satisfaction after hemipelvectomy for pelvic tumors. Surg Oncol. 2026 Mar 6;66:102394. doi: 10.1016/j.suronc.2026.102394. Epub ahead of print. PMID: 41806471.
- Gonzalez MR, Rizk PA, Lozano-Calderon SA. Treatment Success of Periprosthetic Joint Infections in Oncologic Endoprostheses After Standardization of Surgical Strategies-A Systematic Review of the Literature. J Am Acad Orthop Surg. 2026 Mar 15;34(6):e934-e945. doi: 10.5435/JAAOS-D-25-00523. Epub 2025 Sep 24. PMID: 40991858.
Recent Presentations
2026:
American Academy of Orthopaedic Surgeons Annual Meeting, New Orleans, Louisiana
Paper Presentation
- Chose C, Lazarides A, Binitie O, Joyce D, Karadimas T, Hederick L, Griffin A, Tsoi K, Lozano Calderon SA*, Wunder J, Connolly JJ, Ferguson P, Cummings CDoes Staged Resection with Temporizing Wound Vacuum Influence Local Recurrence Risk? A Multi-Institutional Matched Cohort Analysis
- Ribbert A, Gonzalez MR, Connolly JJ, Newman ET, Raskin KA, Lozano Calderon SA*Comparison of Reoperation and Local Recurrence Rates Between Metastasectomy, Intralesional Resection, or Stabilization Alone in the Treatment of Bone Metastases from Renal Cell Carcinoma
OrthoLive Presentation
- Lee S, Connolly JJ, Gonzalez MR, Lozano Calderon SACentralization of Sarcoma Care Improves Outcomes Despite Poorer Presentation: A Systematic Review and Meta-Analysis
Poster Presentation
- Arman Kishan, Jeffrey Wang, Harmon Khela, Gergo Merkely, Shyam Kurian, Santiago Lozano Calderon*, Nicholas Alfonso, Anthony UngerGLP-1 Receptor Agonists and Total Hip Arthroplasty Outcomes: A BMI-Stratified Cohort Analysis
- Lee S, Connolly JJ, Gonzalez MR, Lozano Calderon SA*Centralization of Sarcoma Care Improves Outcomes Despite Poorer Presentation: A Systematic Review and Meta-Analysis
ePoster Presentation
- Connolly JJ, Hederick LL, Goh M, Gonzalez MR, Halur S, Aso A, Lozano Calderon SA*A Comparison of Acetabular Augmentation and Photodynamic Nail Stabilization for Complex Oncologic Total Hip Arthroplasty
- Werenski JO, Connolly, JJ, Anderson ME, Gebhardt M, Lozano Calderon SA*, Gonzalez MR, Pandey S, Heidkamp MPediatric Giant Cell Tumor of Bone
- Arman Kishan, Harmon Khela, Jeffrey Wang, Santiago Lozano Calderon, Nicholas Alfonso, Gergo Merkely, Hayden Box, Ansh KishanImpact of Obesity and Race on 90-Day Postoperative Complications Following Total Hip and Knee Arthroplasty: A Retrospective Cohort Study
European Musculo-Skeletal Oncology Society, Estoril, Portugal
Oral Presentation
- Bosman AF, Ubong SE, Bedi ADS, Werenski JO, Gonzalez MR, Lozano-Calderon SADoes Adding Calcium Sulfate Beads Lead to Higher Treatment Success Rates in Megaprosthetic Joint Infections?
- Bedi ADS, Ubong SE, Kerimo ER, Gonzalez MR, Jutte PC, Lozano-Calderon SAResection Strategy Rather Than Reconstruction Type Influences Functional Outcomes After Oncologic Extrarticular Knee Resection
- Ballatori SE, Ubong SE, Bedi ADS, Goh MH, Gonzalez MR, Girgis AG, Lozano-Calderon SALymph Node Metastases In Soft Tissue Sarcoma: A Population-Based Analysis Of 65,538 Patients
- Ubong SE, DiGiovanni WH, Bedi ADS, Kerimo ER, Lozano-Calderon SAPhotodynamic Nail Fixation Provides Durable Stabilization For Pelvic Metastases Despite Local Disease Progression
ePoster Presentation
- Kerimo ER, Moncho JS, Halur S, Gonzalez MR, Lozano-Calderon SASustained Patient-Reported Improvements Following Minimally Invasive Photodynamic Nail Stabilization of The Pelvis
- Ribbert A, Gonzalez MR, Ubong SE, Bedi ADS, Lozano-Calderon SALong Term Effects of Surgical Approach Selection in Renal Cell Carcinoma Apprendicular Bone Metastases
2025:
34th Annual Musculoskeletal Infection Society Meeting, Durham, NC
Poster Presentation
- Goh MH, Rabiner RA, Lozano-Calderon SA*, Chen AFA Novel Isotropic Optical Fiber: Antimicrobial Effect of Blue Light on Drug Resistant Organisms
Musculoskeletal Tumor Society Annual Meeting, Chicago, IL
Poster Presentations
- Omurzakov A, Rampam S, Gonzalez MR, Lozano-Calderon SA*What is the Incidence and Non-Union Rates of Radiation-Associated Fractures? - A Systematic Review of the Literature
- Goh MH, Rabiner RA, Lozano-Calderon SA*, Chen AFA Novel Isotropic Optical Fiber: Antimicrobial Effect of Blue Light on Drug Resistant Organisms
American Academy of Orthopaedic Surgeons Annual Meeting, San Diego, CA
Poster presentations
- Patel N, Werenski JO, Gonzalez MR, Clunk MJ, McCadden MR, Richard A, Chebib I, Hung YP, Nielsen GP, Lozano-Calderon SA*Does Tumor Necrosis Impact Prognosis in Chondroblastic and Osteoblastic Osteosarcoma? – A Study from a Large Tertiary Care Academic Center
- Patel N, Werenski JO, Gonzalez MR, Clunk MJ, McCadden MR, Richard A, Chebib I, Hung YP, Nielsen GP, Lozano-Calderon SA*Does Tumor Necrosis Impact Prognosis in Chondroblastic and Osteoblastic Osteosarcoma? – A Study from a Large Tertiary Care Academic Center
- Gonzalez MR, Werenski JO, Gebhardt MC, Ghert M, Lozano-Calderon SA*, on behalf of the PARITY Investigators: How Do the Functional Outcomes Vary Based on Ethnicity and Sex Following Tumor Resection and Endoprosthetic Reconstruction? – A Secondary Analysis from the PARITY trial
- Werenski JO, Girgis A, Galoaa B, Gonzalez MR, Lozano-Calderon SA*Development and External Validation of Machine Learning Algorithms for Survival Prediction in Synovial Sarcoma
- Connolly JJ, Gonzalez MR, Goh GS, Lozano-Calderon SA*Microbiological Profile of Prosthetic Joint Infections in Orthopaedic Oncology
37th European Musculoskeletal Oncology Society (EMSOS) Meeting, Padova, Italy
Podium Presentations
- Connolly JJ, Hederick LL, Gonzalez MR, Jejurikar NS, Ballatori SE, Lozano-Calderon SA*Five-year follow-up on wound VAC temporization strategy pending final negative margin achievement in myxofibrosarcoma
- Gonzalez MR, Okay E, Werenski JO, Connolly JJ, Pfeiffer A, Newman ET, Raskin KA, Lozano-Calderon SA*What Are the Long-Term Clinical and Functional Outcomes After Hemicortical Allograft Reconstruction for Primary Bone Tumors?
- Galoaa BM, Girgis AG, Gonzalez MR, Lozano-Calderon SA*Advancing Prognostics in Oncology: Machine Learning Models for Predicting 2-Year and 5-Year Survival Rates in Patients with Undifferentiated Pleomorphic Sarcoma
- Gonzalez MR, Werenski JO, Gebhardt MC, Ghert M, Lozano-Calderon SA*, on behalf of the PARITY InvestigatorsHow Do the Functional Outcomes Vary Based on Ethnicity and Sex Following Tumor Resection and Endoprosthetic Reconstruction? – A Secondary Analysis from the PARITY trial
- Gonzalez MR, Kuthiala R, Newman ET, Raskin KA, Lozano-Calderon SA*What Is the Diagnostic Performance of the International Consensus Meeting Preoperative Minor Criteria in Megaprosthesis Periprosthetic Joint Infections?
- Lozano-Calderon SA*, Gonzalez MR, Werenski JO, Connolly JJ, Hederick LL, Quinn K, Freiberger D, Raskin KAA Prospective Study of the IlluminOss Photodynamic Nail System for Pelvic Stabilization of Impending and Actual Fractures from Metastatic Bone Disease, Multiple Myeloma, and Primary Bone Lymphoma
- Lizcano JD, Gonzalez MR, Pfeiffer AM, Lozano-Calderon SA*Postoperative Opioid Consumption Trends After Oncologic Endoprosthetic Reconstruction of the Lower Limb
Poster Presentations
- Goh MH, Jejurikar N, Gonzalez MR, Lozano-Calderon SA*Augmentation of Osteoarticular Allograft Reconstruction with Photodynamic Nail for the Management of Primary or Recurrent Aggressive Giant Cell Tumor in the Distal Radius
- Goh, MH, Grewal RS, Gonzalez MR, Lim PL, Girgis A, Melnic CM, Bedair HS, Lozano-Calderon SA*What Are the Postoperative Outcomes of Total Knee Arthroplasty Performed for Neoplastic Indications and How Do They Compare Against TKAs Performed for Osteoarthritis? - A Matched Cohort Study
- Goh MH, Ballatori SE, Gonzalez MR, Lozano-Calderon SA*Management of Impending and/or Pathologic Fractures of the Proximal Radius in the Setting of Metastatic Bone Disease with an Intramedullary Photodynamic Nail
51st International Skeletal Society (ISS) Meeting, Lisbon, Portugal
Podium Presentations
- Hsin Chen Y, Bazanjani S, Wange Z, Bauer F, Smith G, Saraee M, Pianykh O, Hung Y, Palmer W, Gonzalez MR, Lozano-Calderon SA*Classification and Differentiation of Myxoid Liposarcoma and Myxoma With Machine Learning
- Lozano-Calderon SA*, Gonzalez MR, Kuthiala R, Newman ET, Raskin KAWhat is the Diagnostic Performance and Accuracy of Serum Inflammatory Biomarkers and Synovial Fluid Analysis in Megaprosthesis Periprosthetic Joint Infections?
- Lozano-Calderon SA*, Gonzalez MR, Okay E, Werenski JO, Silva-Mancera S, Connolly JJ, Pfeiffer A, Duggan J, Newman ET, Raskin KA, Ortiz-Cruz EWhat are the Long-Term Clinical and Functional Outcomes After Intercalary Allograft Reconstruction for Oncologic Indications?
Poster Presentations
- Gonzalez MR, Goh MH, Werenski JO, Gebhardt MC, Ghert M, Lozano-Calderon SA*How do the Functional Outcomes Vary Based on Ethnicity and Sex Following Tumor Resection and Endoprosthtic Reconstruction? - A Secondary Analysis from the Parity Trial
- Gonzalez MR, Okay E, Werenski JO, Connolly JJ, Pfeiffer AM, Ortiz-Cruz EJ, Lozano-Calderon SA*What are the Long-Term Clinical and Functional Outcomes After Hemicortical Allograft Reconstruction for Primary Bone Tumors?
- Girgis AG, Galoaa BM, Gonzalez MR, Lozano-Calderon SA*Predicting Long Term Survival in Myxofibrosarcoma Using Machine Learning: A Study of 2- and 5-Year Outcomes
30th Connective Tissue Oncology Society Annual Meeting, Boca Raton, Florida
Poster Presentations
- Kobald SA, Connolly JJ, Gonzalez MR, Piotrowska Z, Lin JJ, Wang D, Lozano-Calderon SA*Impact of tyrosine kinase inhibitor therapy on bone progression in patients with driver-mutated metastatic non-small cell lung cancer with de novo bone metastases
- Yung Hsin Chen, Soheil Bazanjani, Wang Zhe, Tara Ossiani, Yin P. Hung, Mo Saraee, Marcos Gonzalez, Joseph Connolly, Abigail Chen, Melissa Viator, Andrew Sharp, Oleg Pianykh, Fabian Bauer, Lucy Hederick, Santiago Lozano-Calderon*Differentiation of Myxoma and Myxoid Liposarcoma Based on Radiomics Phenotypes
- Hederick LL, Goh MH, Ibáñez-Navarro A, Halur SR, Miller AR, Connolly JJ, Lozano-Calderón SA*Does Osteochondroma Cartilage Cap Thickness Affect the Rate of Malignant Transformation? A Retrospective Cohort Study
- Vennik AMF, Gonzalez MR, Hopman A, Hederick L, Connolly JJ, Ziljstra I, Chang CY, Lozano-Calderon SA*, Verspoor FGMRisk Factors for Recurrence and Complications of CT-guided Radiofrequency Ablation for the Treatment of Osteoid Osteoma: A Multi-Institutional Analysis
- Mendez-Pino E, Connolly JJ, Goh M, Lozano-Calderon SA*Acute Pathological Long Bone Fractures: Weekend Versus Weekday Variations and their Clinical Impact
- Lee SK, Connolly JJ, Gonzalez MR, Lozano-Calderon SA*Centralization of Sarcoma Care Improves Outcomes Despire Poorer Presentation: A Systematic Review and Meta-Analysis
- Bazanjani S, Zhe W, Hung Y, Saree M, Connolly J, Gonzalez M, Chen A, Ossiani T, Viator M, Sharp A, Pianykh O, Bauer F, Hederick L, Moncho J, Kerimo E, Halur S, Lozano-Calderon S*, Chen YHClassification and Differentiation of Myxoid Liposarcoma and Myxoma with Machine Learning
- Connolly JJ, Hederick LL, Goh MH, Halur SR, Aso A, Gonzalez MR, Lozano-Calderon SA*A comparison of acetabular augmentation and photodynamic nail stabilization for complex oncologic total hip arthroplasty
- Werenski JO, Connolly JJ, Pandey SR, Gonzalez MR, Gebhardt MC, Anderson MA, Lozano-Calderon SA*Pediatric Giant Cell Tumor: Local Recurrence Rates Are Comparable Regardless of Physis Status
- Girgis AG, Galoaa BM, Goh MH, Gonzalez MR, Lozano-Calderon SA*Bias or Best Fit? A Comparative Analysis of SEER and NCDB Datasets in Single-Model
- Girgis AG, Galoaa BM, Goh MH, Gonzalez MR, Lozano-Calderon SA*Development and External Validation of a Machine Learning Algorithm to Predict Overall Survival in Patients with Pelvic or Appendicular Liposarcoma
- Ballatori SE, Gonzalez MR, Goh MH, Girgis AG, Lozano-Calderon SA*Lymph Node Metastases in Soft Tissue Sarcoma: A Comparative Analysis of the SEER and NCDB databases
- Lozano-Calderon SA*, Frazee K, Connolly JJ, Pal R, Krishnamoorthy M, Werenski JO, Hederick LL, Moncho J, Hung YP, Kumar ATNIntraopererative Bone and Soft Tissue Tumor Margin Identification with Fluorescence Lifetime (FLT) Imaging
- Lozano-Calderon SA*, Galoaa BM, Werenski JO, Connolly JJ, Bowers J, Lietz C, Spentzos DExtraskeletal Osteosarcoma: MicroRNA Patterns Provide Insights Into Similarities and Contrasts with Other Sarcomas
- Skornja I, Gonzalez MR, Hederick LL, Newman ET, Raskin KA, Lozano-Calderon SA*Treatment Success Rate after Surgical Management of Periprosthetic Joint Infections in Oncologic Proximal Tibia Reconstruction
Musculoskeletal Tumor Society, Mexico City, Mexico
Poster Presentation
- Ribbert AJG, Gonzalez MR, Connolly JJ, Newman ET, Raskin KA, Lozano-Calderon SAComparison of Reoperation and Local Recurrence Rates Between Metastasectomy, Intralesional Resection, or Stabilization Alone in the Treatment of Bone Metastases from Renal Cell Carcinoma
- Kobald SA, Connolly JJ, Gonzalez MR, Piotrowska Z, Lin JJ, Wang D, Lozano-Calderon SAImpact of tyrosine kinase inhibitor therapy on bone progression in patients with driver-mutated metastatic non-small cell lung cancer with de novo bone metastases
- Skornja I, Gonzalez MR, Hederick LL, Newman ET, Raskin KA, Lozano-Calderon SATreatment Success Rate after Surgical Management of Periprosthetic Joint Infections in Oncologic Proximal Tibia Reconstruction
- Vennik AMF, Gonzalez MR, Hopman A, Hederick L, Connolly JJ, Ziljstra I, Chang CY, Lozano-Calderon SA, Verspoor FGMRisk Factors for Recurrence and Complications of CT-guided Radiofrequency Ablation for the Treatment of Osteoid Osteoma: A Multi-Institutional Analysis
- Hederick LL, Goh MH, Ibáñez-Navarro A, Halur SR, Miller AR, Connolly JJ, Lozano-Calderón SADoes Osteochondroma Cartilage Cap Thickness Affect the Rate of Malignant Transformation? A Retrospective Cohort Study
- Werenski JO, Connolly JJ, Pandey SR, Gonzalez MR, Gebhardt MC, Anderson MA, Lozano-Calderon SAPediatric Giant Cell Tumor: Local Recurrence Rates Are Comparable Regardless of Physis Status
Active Protocols
Learn more about our active protocols. (updated August 2025)
How to Apply
The Musculoskeletal Oncology Fellowship participates in the sfmatch (Residency and Fellowship Match Services) program.
How to reach us
For more information about this Fellowship opportunity:
secondary
phone
Call: 617-724-8801
6177248801
tertiary
email
Email: fviazzoli@mgh.harvard.edu
fviazzoli@mgh.harvard.edu