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MGH Center for Translational Pain Research

The Center is a combined basic science and clinical research facility and focuses on translational research in pain medicine and opioid therapy.
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Email: jmao@mgh.harvard.edu
jmao@mgh.harvard.edu
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Overview

The Massachusetts General Hospital Center for Translational Pain Research is dedicated to bridging the gap between basic science pain research and clinical pain management.

Research Projects

  • Cellular and molecular mechanisms of nociception and pain including neuropathic pain, opioid tolerance, dependence and addiction, and opioid-induced hyperalgesia
  • Chronic pain as a system-based clinical condition
  • Pharmacological and interventional management of conditions such as complex regional pain syndrome, post-herpetic neuralgia, diabetic neuropathy, osteoarthritis, fibromyalgia, and more.
  • Opioid-induced hyperalgesia and its management
  • Brain mechanisms of interactions between pain and pain-related comorbidities such as depression, anxiety and addiction
  • Role of endogenous cannabinoids in the modulation of neuropathic pain
  • Role of central glucocorticoid receptors and glutamatergic receptors in the mechanisms of pain and opioid tolerance
  • Peripheral and central mechanisms of burn injury-induced pain and radicular back pain
  • Preclinical drug development for pain treatment
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Find our More about Clinical Studies in the CIMR
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Research Team

Lucy Chen, MD
Associate Professor, Massachusetts General Hospital and Harvard Medical School
Email address: LLCHEN@mgh.harvard.edu
Jianren Mao, MD PhD
Professor, Massachusetts General Hospital and Harvard Medical School
Email address: jmao@mgh.harvard.edu

Publications

View publications

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How to reach us

Contact us with inquiries about ongoing studies, collaboration opportunities, or lab resources.
tertiary
email
Email: jmao@mgh.harvard.edu
jmao@mgh.harvard.edu
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