MGH Cardiac Psychiatry Research Program
Email: ReachForHealth@MGH.HARVARD.EDU
Email: TheBEHOLDStudy@partners.org
Email: thedreamstudy@mgb.org
Overview
The MGH Cardiac Psychiatry Research program’s work focuses on the connections between mental health, behavior, and medical health in patients with heart disease and other chronic medical conditions. Our research focuses on developing innovative, remotely delivered treatments in three areas:
Promoting well-being and engagement in healthy behaviors, like physical activity.
Positive psychological states, like optimism, positive affect, and self-efficacy, are associated with improved health and with greater engagement in healthy behaviors, such as physical activity and a healthy diet. Based on this idea, our team has developed several remotely delivered interventions to promote well-being and engagement in healthy behaviors in individuals with medical problems, such as type 2 diabetes and heart failure.
We are performing ongoing studies to determine whether phone-delivered versions of these programs may affect biology, health behaviors, and key cardiac outcomes. We are also working to adapt these positive psychological interventions to patients with other medical populations, such as those with metabolic syndrome, irritable bowel syndrome, or cancer, and in those who have undergone weight loss surgery.
In addition to our phone-delivered programs, we have developed programs that utilize other methods of communication, including text messages, podcasts, and artificial intelligence-based messaging, to deliver content to promote well-being and engagement in healthy behaviors.
Identifying and treating depression and anxiety disorders in individuals with cardiovascular disease.
Depression and anxiety have been identified as risk factors for poor cardiac outcomes and death, independent of traditional cardiac risk factors such as high blood pressure, smoking or diabetes. Unfortunately, depression and anxiety go unrecognized and untreated in the vast majority of patients with heart disease, despite the existence of safe and effective treatment. We have performed two randomized trials of “collaborative care” interventions for individuals with heart disease and depression or anxiety disorders. These programs were associated with improvements in depressive symptoms, function, and quality of life.
Optimizing mental and physical health prior to surgery.
Major surgical procedures can be lifesaving but often carry risks of complications. Both psychological and behavioral factors can increase the risk of developing complications following surgery. We are developing innovative, multidisciplinary programs to better prepare individuals mentally and physically to undergo surgery, with the goal of promoting a smoother recovery following their surgical procedures.
In all of the programs we develop, our goal is to help people to live happier and healthier lives.
Research Projects
Boosting Emotional Well-being and Happiness in Outpatients Living with Diabetes (BEHOLD)
A novel psychological-behavioral intervention to promote physical activity in type 2 diabetes; National Institute of Diabetes and Digestive and Kidney Diseases (1R01DK133185)
This is a randomized controlled trial (goal N=280) to test the efficacy of an 8-week, phone-based, positive psychology-motivational interviewing intervention (BEHOLD) to promote physical activity in patients with type 2 diabetes. The BEHOLD program will be compared to a motivational interviewing based educational condition, with a primary outcome of moderate to vigorous physical activity. Principal Investigator (PI): Jeff Huffman, M.D.
Positive Emotions after Acute Coronary Events (PEACE V)
A novel psychological-behavioral intervention to promote physical activity in patients with acute coronary syndrome; National Heart Lung and Blood Institute (1R01HL113272)
This is a randomized controlled trial (goal N=280) to test the efficacy of a 12-week, phone-based, positive psychology-motivational interviewing intervention (PEACE) to promote physical activity in patients with acute coronary syndrome (unstable angina or myocardial infarction). The PEACE program will be compared to treatment as usual, with a primary outcome of moderate to vigorous physical activity. Principal Investigator (PI): Jeff Huffman, M.D.
Reach for Health: Researching Emotions and Cardiac Health
A Novel Behavioral Intervention to Promote Adherence in Heart Failure; National Heart, Lung, and Blood Institute (1R01HL155301)
This is a randomized trial (goal N=280) to examine the efficacy of a 12-week, phone-delivered, combined positive psychology-motivational interviewing intervention (“Reach for Health”) to promote health behavior adherence in patients with heart failure. The Reach for Health program will be compared to a motivational interviewing-based control condition, and the primary outcome will be a measure consisting of physical activity, sodium excretion, and medication adherence. Principal Investigator (PI): Christopher Celano, M.D.
WISH 2.0 Pilot Randomized Controlled Trial
A Positive Psychology Intervention for Irritable Bowel Syndrome; National Institute of Diabetes and Digestive and Kidney Diseases (K23DK138875)
This study is a pilot, randomized controlled trial (goal N=50) to evaluate the feasibility, acceptability, preliminary effects, and candidate gut-brain mechanisms of a novel, 9-week, phone-based behavioral health intervention for irritable bowel syndrome (IBS). Principal Investigator (PI): Elizabeth Madva, M.D.
GOALS-M: Adapting a positive emotion-based physical activity intervention for individuals taking incretin-based medications for weight loss
This study is a single-arm proof-of-concept trial (N=19) designed to refine and test initial feasibility and acceptability of GOALS-M, a physical activity intervention for individuals taking incretin-based medications for weight loss. The 10-week phone-based intervention uses positive psychological and behavioral tools to increase positive affect and physical activity. Principal Investigator (PI): Emily Feig, Ph.D.
Developing Resiliency using AI-based Messaging: The DREAM pilot study (DREAM)
This randomized, controlled pilot trial (goal N=20) aims to examine the feasibility, acceptability, and preliminary efficacy of the DREAM program, an 8- week, interactive, message-based intervention to promote physical activity and wellbeing in adults with type 2 diabetes. In the program, participants will complete positive psychology and motivational interviewing activities during weekly messaging sessions along with a mid-week check-in. Principal Investigator (PI): Christopher Celano, M.D.
Prehabilitation for aortic aneurysm surgery: Proof-of-concept trial (Ready for Recovery)
This is a single arm, proof-of-concept trial (goal N=10) to examine the feasibility, acceptability, and preliminary efficacy of the Ready for Recovery program, a 6-week, multicomponent, phone-delivered prehabilitation intervention for individuals undergoing elective aortic aneurysm repair. In Ready for Recovery, a multidisciplinary team screens individuals awaiting surgery for risk factors for post-surgical complications and then collaboratively develops a tailored prehabilitation plan to optimize medical and psychological status prior to surgery. Principal Investigator (PI): Christopher Celano, M.D.
Move with Meaning Pilot Trial
A text- and audio-based intervention to promote physical activity in midlife
This is a randomized, wait-list controlled pilot trial (goal N=30) to examine the feasibility, acceptability, and preliminary efficacy of Move with Meaning, an 8-week text message- and audio-based intervention to promote physical activity in 30 midlife adults with low physical activity. Each week, participants will listen to a 20-minute audio session that provides instruction and encouragement related to physical activity and set a weekly goal through interactive text messages. Principal Investigator (PI): Christopher Celano, M.D.
Recently Completed
Gaining Optimism After Weight Loss Surgery (GOALS)
Randomized Controlled Trial of a Positive Psychology-based Intervention to Increase Physical Activity After Bariatric Surgery ; National Institutes of Health: National Heart, Lung, and Blood Institute (K23HL148017)
This study aimed to increase physical activity and psychological well-being in adults who have recently had metabolic and bariatric surgery. We adapted a positive psychology-motivational interviewing telephone counseling intervention for the needs of this population via qualitative interviews and a proof-of-concept study. We then tested the intervention in a pilot randomized controlled trial to examine feasibility, acceptability, and preliminary efficacy on physical activity, positive affect, and other outcomes in adults who recently had metabolic and bariatric surgery. Principal Investigator (PI): Emily Feig, Ph.D.
Research Team
Jeff Huffman, MD
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Dr. Jeff Huffman is the Director of the Cardiac Psychiatry Research Program (CPRP) and a Professor of Psychiatry at Harvard Medical School (HMS). He currently serves as principal investigator for multiple projects and has been awarded grants from the American Heart Association, American Diabetes Association, Templeton Foundation, American Foundation for Suicide Prevention, and National Institutes of Health (NHLBI, NINR, and NIDDK). He has over 300 peer-reviewed publications and has mentored post-doctoral psychology fellows, junior psychiatrist and psychologist faculty, medical students, psychiatry residents, research fellows, psychologists, social workers, and he received the 2017 MGH Psychiatry Outstanding Research Mentor Award and the 2019 HMS Stuart Hauser Mentorship Award. His areas of interest include the impact of psychiatric illness on patients with cardiac disease, and the development and use of positive psychological interventions in a wide range of populations.
Christopher Celano, MD
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Dr. Christopher Celano is an attending psychiatrist at Massachusetts General Hospital, an Associate Professor of Psychiatry at Harvard Medical School, and the Associate Director of the CPRP. He is the Principal Investigator of Reach for Health, an R01-funded trial to examine the efficacy of a psychological intervention to improve health behaviors in patients with heart failure, and he serves as the project director of health behavior trials in patients with coronary artery disease and diabetes. He has published over 120 articles and has received funding from the National Heart, Lung, and Blood Institute, Harvard Medical School, and the Lee Kum Sheung Center for Health and Happiness. His areas of interest include the impact of depression and anxiety on cardiac health, the use of technology to deliver health behavior interventions, the promotion of positive psychological well-being and health behavior adherence, and the development of programs to promote recovery following surgery.
Elizabeth Madva, MD
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Dr. Elizabeth Madva is an Assistant Professor of Psychiatry at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) with clinical and research expertise in the disorders of gut-brain interaction, also known as functional GI disorders. After completing her psychiatry residency and consultation-liaison psychiatry fellowship training at MGH, she developed a psychiatry clinic embedded within MGH gastroenterology where she provides clinical care for patients with DGBI and supervises trainees from across disciplines. Her clinical research focuses on the development of novel behavioral health interventions for the DGBI as well as on the use of psychiatric medications to target gut symptoms. Her research has been supported by the HMS Dupont Warren and Livingston Fellowship Awards, and is currently supported by a Career Development Award through the National Institute of Diabetes and Digestive and Kidney Diseases.
Emily Feig, PhD
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Dr. Emily Feig is a clinical psychologist at MGH and Assistant Professor of Psychology at Harvard Medical School. She is a recipient of a K23 award from the National Heart, Lung, and Blood Institute to develop and test a physical activity intervention for patients who have had bariatric surgery. Her research interests focus on better understanding and addressing internalized weight bias, and on improving adherence to health behaviors in individuals with obesity-related chronic disease. Clinically, Dr. Feig specializes in cognitive behavioral and acceptance-based therapies targeting anxiety, depression, and disordered eating.
Christina Massey, PhD
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Dr. Christina Massey is a clinical psychologist at MGH and Instructor at Harvard Medical School. She joined the CPRP in 2017 and serves as an interventionist and clinical supervisor across multiple positive psychology and motivational interviewing-based studies with the CPRP. She completed her doctoral training in clinical psychology with a specialization in forensic psychology at the CUNY Graduate Center at John Jay College of Criminal Justice and her doctoral internship at MGH. Her clinical interests involve integrative psychotherapy for depression, anxiety, and trauma spectrum disorders as well as diagnostic and forensic assessment and evaluation.
Rachel Millstein, PhD, MHS
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Dr. Millstein is a clinical psychologist at MGH and Assistant Professor in Psychiatry at Harvard Medical School. She is the recipient of a National Institutes of Health K23 award to develop a multilevel positive psychology intervention to promote health behaviors, in particular physical activity, among patients with metabolic syndrome. Dr. Millstein studies coping with and preventing chronic health conditions. Her clinical and research work focus on lifestyle modifications for chronic disease management.
Wei-Jean Chung, PhD
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Dr. Chung is a clinical psychologist at MGH and Instructor at Harvard Medical School. She received her doctoral training in clinical psychology at Adelphi University prior to completing her doctoral internship and postdoctoral fellowship at MGH. She is an interventionist for studies being performed at the CPRP. In addition to her involvement with the CPRP, she is the Co-Director of Primary Care Psychiatry. Her clinical practice involves caring for people with serious mental illness and complex personality organization across multiple clinical services within MGH Psychiatry, including Primary Care Psychiatry, the Dialectical Behavioral Therapy Team, and the MGH inpatient psychiatry service.
Hermioni L. Amonoo, MD, MPP
Massachusetts General Hospital, Brigham and Women’s Hospital, Dana-Farber Cancer Institute
Dr. Amonoo is a physician-scientist and staff physician the Departments of Psychiatry at Brigham and Women’s Hospital (BWH) and Psychosocial Oncology and Palliative Care at the Dana-Farber Cancer Institute (DFCI). She is also an Associate Professor of Psychiatry at Harvard Medical School and the Associate Training Director of the Brigham and Women’s Hospital-Harvard Medical School Adult Psychiatry Residency Training Program. Dr. Amonoo’s program of research aims to understand the wellbeing needs of vulnerable cancer populations, especially those with hematologic malignancies undergoing stem cell transplantation, to inform the development of novel psychological and digital interventions for patients with cancer and their caregivers. Her research has been consistently funded by Harvard Medical School, Brigham and Women’s Hospital/Brigham Research Institute, National Cancer Institute, the Oppenheimer Family Foundation, American Society for Hematology, and the Robert Wood Johnson Foundation. She is also an active co-investigator for several trials in the CPRP.
Megan Bidgood, BA
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Megan Bidgood is a Clinical Research Coordinator I at the Cardiac Psychiatry Research Program. She assists with a variety of the positive-psychology and motivational-interviewing (PP-MI) studies including Reach for Health, GOALS-M, and WISH, as well as an observational study to identify predictors of response to collaborative care treatment for anxiety and depression. Megan graduated with a BA in Psychology and Human Development from Connecticut College in 2025. Her research interests focus on promoting psycho-social wellbeing through mind-body interventions, especially in those with chronic health conditions. Megan plans to pursue a career in Clinical Psychology, where her continuous involvement in research can inform her clinical practice.
Isabella Henneman, BS
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Isabella Henneman is a clinical coordinator II at the Cardiac Psychiatry Research Program. She assists with the Reach for Health and Ready for Recovery studies. Isabella graduated with a BS in Psychology from Michigan State in 2022 and is interested in researching mechanisms of physical and mental health and wellbeing in populations dealing with stress and chronic health conditions.
Ruby Kaplan, BA
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Ruby Kaplan is a Clinical Research Coordinator I at the Cardiac Psychiatry Research Program. She assists with multiple studies of positive psychology and motivation interviewing studies including PEACE, BEHOLD, and Move with Meaning. Ruby earned a BA with honors in Psychology and Brain Sciences from Washington University in St. Louis in 2025. Ruby plans to pursue a career in Clinical Psychology.
Emmett McGranaghan, BS
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Emmett McGranaghan is the primary research coordinator for the PEACE Study (a positive psychology intervention for patients with acute coronary syndrome) and the WISH Study (a positive psychology intervention for patients with irritable bowel syndrome). Emmett graduated summa cum laude from Trinity College in 2024 with a degree in Biology and a certificate in Global Health Humanities. In addition to his position at the CPRP, Emmett collaborates on research projects with the MGH Neurointestinal Health Center, works as a Youth Mentor through the Post-Bacc Association, and volunteers in the MGH NICU with the Baby Cuddler program.
Talyn Steinmann BSEd
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Talyn Steinmann is a Clinical Research Coordinator at the Cardiac Psychiatry Research Program. She assists with various positive psychology and motivational interviewing (PP-MI) and prehabilitation studies including BEHOLD, DREAM, and Ready for Recovery. Talyn graduated from the University of Virginia in 2025 with majors in Global Public Health and Kinesiology. Her research interests focus on promoting health behavior adherence in individuals with chronic disease, the interrelation of physical and mental health, healthy aging, preventative approaches to health, and the translation and implementation of research on community, systems, and policy levels.
Maddie Shapiro, LCSW
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Maddie Shapiro, LCSW is a Clinical Social Worker at the CPRR, where she serves as a study interventionist on the BEHOLD and PEACE programs. In this role, she works to enhance participants’ physical activity levels using approaches grounded in positive psychology and motivational interviewing. Maddie earned her Bachelor of Arts in Psychology, with a minor in Russian Language, from Trinity College in Hartford, CT, graduating summa cum laude in 2022. Her undergraduate thesis examined changes in college students’ substance use habits and motivations during the COVID-19 pandemic. She went on to receive her Master of Social Work from Boston University in 2024. Prior to joining the CPRR, Maddie interned at the New England Conservatory of Music’s counseling center, where she provided individual therapy to college students.
Sara Portela, LCSW
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Sara Portela, LCSW, is a clinical social worker at the CPRP. She primarily works as a study interventionist on multiple studies, including PEACE and BEHOLD, aiming to improve participants’ physical activity levels utilizing positive psychology and motivational interviewing modalities. Sara graduated magna cum laude with a dual Bachelor of Arts in Psychology and Sociology from Boston University in 2021, where she was a research assistant at the Center for Anxiety and Related Disorders’ Translational Research Program (PI: Michael W. Otto, PhD). She then went on to obtain a Master of Social Work at Boston College in 2023, with a focus on trauma-informed care. Before joining the CPRP, Sara worked as a clinical social worker in the Intensive Care Unit and Emergency Department at Newton-Wellesley Hospital.
Yvonne Woodworth, BA
Massachusetts General Hospital, Cardiac Psychiatry Research Program
Yvonne Woodworth is a Clinical Research Program Project Manager at the CPRP. She graduated from Boston University with a Bachelor of Arts in Psychology. She has been a longtime member of the Department of Psychiatry at MGH, and she joined the CPRP in 2023.
Jai Ahuja, MBBS
Dr. Jai Ahuja is a Research Fellow at the Cardiac Psychiatry Research Program (CPRP) at Massachusetts General Hospital and Harvard Medical School. He is interested in understanding complex psychiatric phenomena through both clinical and research lenses. His interests include digital psychiatry and psychoanalysis, with a particular focus on how emerging technologies and psychodynamic frameworks can inform modern psychiatric practice.
Daniel Schaefer, MD
Dr. Daniel Schaefer is a postdoctoral research fellow at Massachusetts General Hospital and Dana-Farber Cancer Institute and an incoming psychiatry resident at Beth Israel Lahey Health. He did his research doctorate in pediatric oncology at the Dana-Farber Cancer Institute, and his current work focuses on the intersection of psychiatry and medicine, including psychosocial oncology, cardiac psychiatry, and psychedelic-assisted therapies.
Monika Sadlonova, MD
Massachusetts General Hospital, University Medical Center Göttingen
Monika Sadlonova, MD, is a collaborator and consultant to the Cardiac Psychiatry Research Program. She graduated from the fellowship program in psychosomatic consultation-liaison service (´Psychosomatic Medicine and Psychotherapy´) at University of Göttingen Medical Centre in Germany in 2020, where she served as staff physician in psychosomatic consultation-liaison service at the Department of Cardiovascular and Thoracic Surgery (Prof. I. Kutschka) and co-investigator in multicenter TEACH clinical trial (PI - Prof. C. Herrmann-Lingen, ´Blended collaborative care in distressed patients with chronic coronary heart disease´). She obtained training in psychodynamic psychotherapy at Lou-Andreas-Salomé Institute in Göttingen, Germany. Her clinical and research interests fall within the areas of psychosomatic medicine / consultation-liaison psychiatry, with special interests in psychiatric symptoms, psychological interventions, and delirium prevention arising in the context of cardiac surgery and cardiology.
James Januzzi, MD
Massachusetts General Hospital, Harvard Medical School
James Januzzi, MD, is an Associate Professor of Medicine in the Division of Cardiology at Harvard Medical School, and the Director of the Cardiac Intensive Care Unit at Massachusetts General Hospital. He is a well-established researcher at Mass General with over 900 peer-reviewed research publications, over 100 review articles and chapters, and has edited three textbooks. He is internationally known as an expert in the study of biomarkers in patients with heart failure and other cardiac illnesses, and has served as a section editor on the recent American College of Cardiology/American Heart Association clinical practice guidelines for heart failure, and was the lead for the heart failure section for the Universal Definition of Myocardial Infarction Global Task Force. He has served as the primary cardiologist on projects for the CPRP for the past nine years, including collaborative care depression and anxiety management trials in hospitalized cardiac patients, and studies of positive psychological states in persons with heart disease.
Brian Healy, PhD
Massachusetts General Hospital, Harvard Medical School, Harvard School of Public Health
Brian Healy, PhD, is an Assistant Professor in the Department of Neurology at Harvard Medical School, a member of the Biostatistics Center at Massachusetts General Hospital, and an Instructor in Biostatistics at the Harvard School of Public Health. Dr. Healy is also the lead biostatistician for the Mass General Brigham Multiple Sclerosis Center, which is affiliated with Brigham and Women's Hospital. His primary research interest is statistical methods development and application for modeling of multiple sclerosis. He has been working with the CPRP for the past 15 years, and he has participated in the design and analysis of several studies.
Dr. Elyse Park (qualitative research and motivational interviewing): Mongan Institute for Health Policy
Dr. Andrés Bedoya (behavioral interventions)
Dr. Hanna Gaggin (cardiology)
Dr. Bettina Hoeppner (technology use for behavior change), Recovery Research Institute
Dr. Amy Sarma (cardiology)
Dr. Deborah Wexler (endocrinology), Diabetes Clinical Research Center
Mary Larkin, MS, (endocrinology) Diabetes Clinical Research Center
Dr. Matthew Nock, (prediction and prevention of suicide/self-harm), Department of Psychology, Harvard University
Dr. Linda Collins, (novel methods of optimizing and evaluating multicomponent behavioral interventions), The Methodology Center, Penn State University
Dr. Todd Kashdan, (positive psychology and interventions to increase well-being), The Center for Consciousness & Transformation, George Mason University
Dr. Julia Boehm, (positive psychology), Department of Psychology, Chapman University
Bruce Rollman (treatment of depression and anxiety in cardiac patients), University of Pittsburgh Medical Center
Dr. Steven Safren, Department of Psychology, University of Miami
Dr. Evan Kleiman, (identifying risk and resilience factors for suicide,) Department of Psychology, Rutgers University
Dr. Laura Kubzansky and the Lee Kum Shueng Health and Happiness Center
Medical Students:
Gillian Sowden
Chris Doughty
Christina Carr
Kirsti Campbell
Sean Legler
Residents:
Curtis Wittmann
Amy Taylor
Leah Bauer
Keri Oxley
Michael Soule
Faculty/Fellows:
Felicia Smith
Andres Caro
Trina Chang
Giselle Perez-Lougee
Oriana Vesga-Lopez
Laura Suarez
Ana Claudia Villegas
Federico Gomez
Caitlin Adams
Juan Pablo Ospina
Laura Duque-Serrano
Franklin King
Perla Romero
Juan David Sossa
Henry Onyeaka
Juliana Zambrano
Scott Beach
Daniel Arroyo-Ariza
Alexandra Rojas
Alba Carillo
Francisco Barrera
Pia Maria Ghanime
Joyce Meza Venegas
Andres Ramirez
Research Coordinators:
Marguerite Beiser
Rita Seabrook
Shannon Moore
Emma Lenihan
Tina DuBois
Ellie Beale
Ari Albanese
Margot Barclay
Diana Smith
Melanie Freedman
Julia Golden
Carlyn Scheu
Sonia Kim
Regina Longley
Olivia Velasquez
Lauren Harnedy
Jane Jurayj
Audrey Kelly
Liz Daskalakis
Crystal Castillo
Rebecca Karlson
Lily Jacobson
Nikita Acharya
Taylor Claar
Tim Song
Daniel Weber
Julia Fan
Sai Rachakonda
Social Work and Nursing Interventionists:
Rachel Rodman
Stephanie Mahnks
Meaghan Morrison
Beth Pino-Mauch
Rafaela Dos Santos
Maggie Ford
Sophie Staton
Karen Rosenblum
Margaret Bell
Special thanks: Our work has also been generously supported by the esteemed Avery D. Weisman, MD, of the eponymous Massachusetts General Hospital Psychiatry Consultation Service and a long-standing national leader in psychosomatic medicine. His support has allowed the CPRP to continue to investigate the associations between positive and negative emotional states and physical health and well-being, and we are forever indebted.
Publications
Madva EN, Huffman JC, Castillo C, Harnedy LE, Franklin T, Song MT, Burton-Murray H, Healy B, Staller K, Bartels S, Kuo B, Keefer L, Celano CM. A Randomized Waitlist-Controlled Trial of a Positive Psychology Intervention for Irritable Bowel Syndrome: The WISH Proof-of-Concept Trial. Neurogastroenterol Motil. Nov 2025;37(11):e70146.
Celano CM, Jacobson LH, Feig EH, Millstein RA, Chung WJ, Massey CN, Healy BC, Henneman I, Sadlonova M, Acharya NB, Huffman JC. A text message intervention to promote physical activity in midlife: The MASTERY randomized pilot trial. J Psychosom Res. Oct 2025;197:112372.
Sadlonova M, Beach SR, Funk MC, Rosen JH, Ramirez Gamero AF, Karlson RA, Huffman JC, Celano CM. Risk Stratification of QTc Prolongation in Critically Ill Patients Receiving Antipsychotics for the Management of Delirium Symptoms. J Intensive Care Med. Apr 2025;40(4):355-371.
Amonoo HL, Daskalakis E, Wolfe ED, Guo M, Celano CM, Healy BC, Cutler CS, Antin JH, Pirl WF, Park ER, Jim HSL, Lee SJ, LeBlanc TW, El-Jawahri A, Huffman JC. A Positive Psychology Intervention in Allogeneic Hematopoietic Stem Cell Transplantation Survivors (PATH): A Pilot Randomized Clinical Trial. J Natl Compr Canc Netw. Jun 2024;22(2 D)
Feig EH, Szapary C, Harnedy LE, Castillo C, Thorndike AN, Psaros C, Millstein RA, Huffman JC. Using Positive Psychology to Address Emotional Barriers to Physical Activity After Bariatric Surgery: Proof-of-Concept Trial of the Gaining Optimism After Weight Loss Surgery (GOALS) Project. Cogn Behav Pract. May 2024;31(2):189-202.
Celano CM, Healy BC, Jacobson LH, Bell M, Carrillo A, Massey CN, Chung WJ, Legler SR, Huffman JC. An adaptive text message intervention to promote psychological well-being and reduce cardiac risk: The Text4Health controlled clinical pilot trial. J Psychosom Res. Feb 2024;177:111583.
Feig EH, Madva EN, Millstein RA, Zambrano J, Amonoo HL, Longley RM, Okoro F, Huffman JC, Celano CM, Hoeppner B. Can positive psychological interventions improve health behaviors? A systematic review of the literature. Prev Med. Oct 2022;163:107214.
Huffman JC, Golden J, Massey CN, Feig EH, Chung WJ, Millstein RA, Brown L, Gianangelo T, Healy BC, Wexler DJ, Park ER, Celano CM. A positive psychology-motivational interviewing program to promote physical activity in type 2 diabetes: The BEHOLD-16 pilot randomized trial. Gen Hosp Psychiatry. Jan-Feb 2021;68:65-73.
Celano CM, Freedman ME, Harnedy LE, Park ER, Januzzi JL, Healy BC, Huffman JC. Feasibility and preliminary efficacy of a positive psychology-based intervention to promote health behaviors in heart failure: The REACH for Health study. J Psychosom Res. Dec 2020;139:110285.
Huffman JC, Golden J, Massey CN, Feig EH, Chung WJ, Millstein RA, Brown L, Gianangelo T, Healy BC, Wexler DJ, Park ER, Celano CM. A positive psychology-motivational interviewing intervention to promote positive affect and physical activity in type 2 diabetes: The BEHOLD-8 controlled clinical trial. Psychosom Med. Sep 2020;82(7):641-649.
Millstein RA, Huffman JC, Thorndike AN, Freedman M, Scheu C, Kim S, Amonoo HL, Barclay M, Park ER. How Do Positive Psychological Constructs Affect Physical Activity Engagement Among Individuals at High Risk for Chronic Health Conditions? A Qualitative Study. J Phys Act Health. Sep 4 2020;17(10):977-986.
Huffman JC, Feig EH, Millstein RA, Freedman M, Healy BC, Chung WJ, Amonoo HL, Malloy L, Slawsby E, Januzzi JL, Celano CM. Usefulness of a positive psychology-motivational interviewing intervention to promote positive affect and physical activity after an acute coronary syndrome. Am J Cardiol. Jun 15 2019;123(12):1906-1914.
Huffman JC, Mastromauro CA, Beach SR, Celano CM, DuBois CM, Healy BC, Suarez L, Rollman BL, Januzzi JL. Collaborative care for depression and anxiety disorders in patients with recent cardiac events: the Management of Sadness and Anxiety in Cardiology (MOSAIC) randomized clinical trial. JAMA Intern Med. Jun 2014;174(6):927-35.
Huffman JC, Mastromauro CA, Sowden G, Fricchione GL, Healy BC, Januzzi JL. Impact of a depression care management program for hospitalized cardiac patients. Circ Cardiovasc Qual Outcomes. Mar 2011;4(2):198-205.