Ann Romney Center for Neurologic Diseases

Overview

The Ann Romney Center for Neurologic Diseases is a collaborative global pursuit to accelerate treatments, prevention, and cures for five of the world’s most complex neurologic diseases: multiple sclerosis, Alzheimer's disease, ALS (Lou Gehrig’s disease), Parkinson's disease, and brain tumors. The collaborative nature of the Ann Romney Center allows Brigham and Women's Hospital to partner with the medical and scientific communities worldwide in pursuit of the highest level of care while promoting discovery and accelerating the translation of scientific findings into clinical practice.

Comprised of a group of multidisciplinary biomedical research laboratories, the Ann Romney Center applies a wide range of biological methods to elucidate the pathogenesis and treatment of chronic, unsolved neurological diseases.

Research Team

Dennis J. Selkoe, MD
Co-director, Ann Romney Center for Neurologic Diseases
Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School

Dr. Selkoe’s groundbreaking work has identified the fundamental mechanisms underlying the development of Alzheimer's disease (AD), defined forms of amyloid β-protein that have a strong negative effect on neuronal function and on memory, and shown that antibodies to the protein effectively neutralize these adverse effects. His extensive published studies have helped lead to clinical trials of inhibitors of the buildup of the amyloid β-protein, and he is currently examining the detailed basis for neuronal impairment and testing various experimental approaches.

Howard L. Weiner, MD
Co-director, Ann Romney Center for Neurologic Diseases
Research Director, Division of Multiple Sclerosis and Neuro-Immunology, Department of Neurology
Robert L. Kroc Professor of Neurology, Harvard Medical School

A world-renowned expert in the treatment and research of multiple sclerosis, Dr. Weiner's discoveries regarding basic mechanisms of MS have led to the development of new treatment approaches applied worldwide. He is the author of Curing MS and the recipient of the prestigious John Dystel Prize from the American Academy of Neurology for his work in MS.