Cerebrovascular Research Lab

Overview

The Du Laboratory explores the genetic basis of cerebrovascular diseases including cerebral aneurysms, stroke, and arteriovenous malformations via clinical, translational and basic research. Our goal is to apply this knowledge to develop novel diagnostic and therapeutic strategies using state-of-the-art techniques such as gene regulation.

Featured Research

Brain-targeted intranasal delivery of protein-based gene therapy for treatment of ischemic stroke

We demonstrated that a protein-based CRISPR-dCas9 system can be used to target neuroprotective genes as a novel therapy for acute ischemic stroke.

Research Team

Rose Du, MD, PhD
Professor of Neurosurgery, Harvard Medical School and Brigham and Women’s Hospital

Nadia Rai, PhD
Postdoctoral Fellow

Anil Can, MD
Postdoctoral Fellow

Selena-Rae Tirado, MPH
Medical Student

Pranav Samineni, BA
Medical Student

Recent past members

Jianing Zhang, PhD
Jee-Yeon Ryu, PhD
Rosalind Pui Man Lai, MD

Publications

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