Reproductive Endocrinology and Infertility Research

Overview

Mass General Brigham’s Reproductive Endocrinology and Infertility (REI) research spans basic, translational, and clinical science to advance understanding and treatment of infertility, reproductive disorders and hormonal health. Investigators explore the genetics and physiology of reproduction, study IVF outcomes, embryo development, and assisted reproductive technologies using large clinical datasets, artificial intelligence, and laboratory innovation. Investigators develop new diagnostics and therapies for conditions like PCOS and hypothalamic amenorrhea, and engage in cutting-edge work on infertility causes, ovarian function, and reproductive endocrinology. Additional work explores reproductive aging, stem cell and developmental biology, environmental influences on reproductive health, menstrual cycle physiology, and menopause-related conditions This research supports improved fertility care, innovative treatment options, and advances in reproductive medicine across the healthcare system.