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GI Cancers – Daniel C. Chung Laboratory

Our laboratory seeks to gain new insights into the molecular pathogenesis of polyps and tumors of the GI tract and identify novel ways to prevent and screen for these tumors.

Overview

Our research program revolves around GI cancer pathogenesis and cancer screening both in average risk and high risk individuals. Clinical translational studies are focused on identifying new genotype-phenotype correlations in families with hereditary cancer syndromes. Improving the recognition of families with hereditary cancer syndromes and defining the specific cancer risks associated with specific mutations are important goals. Using our hereditary GI cancer family registry, we are well positioned to answer important questions about cancer risk, cancer prevention, and early cancer detection across the spectrum of hereditary gastric, pancreatic, and colon cancers. The field is rapidly evolving, and we seek to enhance the use of genetic information to improve clinical management and cancer screening in these individuals and families.

Research Team

Daniel Chung, M.D.

Medical Co-Director, Center for Cancer Risk Assessment
Director, High-Risk GI Cancer Clinic
Professor of Medicine, Harvard Medical School