Office of Clinical Research
Overview
The Office of Clinical Research at Mass General Brigham provides centralized support to help investigators design, launch, and manage clinical studies. Its services include regulatory compliance, study operations, budgeting, contracting, and oversight, as well as a robust education program and consultations across a wide range of specialties, disciplines, and research areas. By streamlining the research process and offering expert guidance, OCR enables investigators to focus on conducting high-quality, ethical, and efficient clinical research.
Our Services
Our Biostatistics team provides expert statistical support for studies of any size, guiding researchers through study design, protocol development, grant applications, and data analysis for publications and presentations. This service streamlines research and enhances the quality and impact of scientific work.
Biostatistics services are available through the BWH CCI and MGH DCR.
Our Data Management team provides comprehensive support for clinical research, guiding investigators in data planning, collection, storage, and dissemination. Services include implementing data capture systems, designing case report forms (CRFs), managing and validating study databases, reviewing data, and preparing regulatory-ready datasets to ensure accuracy, compliance, and efficiency.
Data Management services are available through the BWH CCI, MGH DCR, and MEE CCRO
Our Project Management team supports all stages of the protocol lifecycle, from preparing study materials and regulatory documentation to assisting with IRB, Ethics Committee, and FDA processes. They train site staff on protocols and Good Clinical Practice, while providing ongoing reporting to keep studies organized, compliant, and on track.
Project Management services are available through the MGH TCRC, MGH DCR, and MEE CCRO
Our Research Coordination team provides investigators with experienced coordinators to support clinical studies across multiple protocols. Services include protocol development, regulatory compliance, participant recruitment, visit coordination, data collection, and training for new or less-experienced research staff, ensuring efficient and high-quality study execution.
Research Coordination services are available through the BWH CCI, MGH TCRC, MGH DCR, and MEE CCRO
Our Clinical Visit Support services assist study teams at every stage of clinical research, from planning to execution. Nurses and Advanced Practice Providers help to develop and operationalize protocols, coordinate visits, perform clinical procedures, monitor participants, and manage sample collection and investigational drug administration, ensuring participant safety, protocol adherence, and accurate data collection across inpatient, outpatient, and off-site settings for both adult and pediatric participant populations.
Clinical Visit Support services are available through the BWH CCI and MGH TCRC.
Our Clinical Monitoring Services ensure studies are conducted safely, accurately, and in compliance with protocols and regulatory requirements. We oversee participant safety, monitor data quality, track study progress, and provide ongoing site support to maintain protocol integrity across all research settings.
Clinical Monitoring services are available through the BWH CCI and MGH DCR, and MEE CCRO.
Our Laboratory Services support clinical research by managing the collection, processing, storage, and shipment of biological samples. We assist with lab protocol implementation and sample analysis procurement, ensure protocol compliance, maintain sample integrity, and uphold high data quality standards, providing reliable and efficient laboratory support for a wide range of studies.
Lab services are available through the MGH TCRC.
Advance your research with expert support across the full study lifecycle. Our multidisciplinary teams and faculty offer 1:1 consultations and practical guidance — helping investigators and study teams conduct high-quality clinical and translational research from concept through execution. Initial consultations (up to 6 hours) are available at no cost.
To submit a consult request, please click here